Guaifenesin Application

Guaifenesin is an expectorant, also known as guaiac, methionate, glycerol guaiac, which can stimulate the gastric mucosal reflex to increase the secretion of bronchial mucosa and reduce sputum. Sticky, making the stick easily cough up. It has disinfection and antiseptic effect, can reduce the odor of sputum, and also has antitussive, antispasmodic and anticonvulsant effects. It is used for chronic bronchitis, cough, lung abscess, bronchiectasis and secondary asthma. Other antitussive and antiasthmatic drugs are combined.

Guaifenesin is absorbed from the gastrointestinal tract and reaches a peak plasma concentration after 1 to 3 hours. Most of it is excreted from the intestines, and a small amount of metabolism to glucuronic acid conjugates is rapidly excreted with urine.

In 2016, it was the 261st most prescribed medication in the United States with more than a million prescriptions.[