L-tert-Leucine can be used for below applications:

• As a key precursor in the synthesis of a chiral phosphinooxazoline ligand, (S)-tert-butylPHOX;
• In the synthesis of chiral copper(II) polymers that can catalyze the kinetic resolution of secondary alcohols by acylation;
• In metal-free tandem radical cyclization reactions to synthesize 6-alkyl/acyl phenanthridines;
• In the preparation of tert-leucine-derived N-acetylthiazolidinethione auxiliary that provides high levels of diastereoselection in acetate aldol reactions with different aldehydes